The Machinery of Life Functions Inside a Very Crowded Cell
- Speaker
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Bridget Carragher, Ph.D.Co-Director, Simons Electron Microscopy Center, New York Structural Biology Center
Adjunct Professor, Biochemistry and Molecular Biophysics, Columbia University
Presidential Lectures are free public colloquia centered on four main themes: Biology, Physics, Mathematics and Computer Science, and Neuroscience and Autism Science. These curated, high-level scientific talks feature leading scientists and mathematicians and are intended to foster discourse and drive discovery among the broader NYC-area research community. We invite those interested in the topic to join us for this weekly lecture series.
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A living cell is an astonishingly complex environment. It is tightly packed with millions of molecular machines that do the work of the cell and provide structure, function and regulation. Over the last five years, electron microscopy (EM) has undergone a revolution. Advancements have catapulted EM to the forefront method for determining the detailed structures of these machines and how they interact inside the densely packed interior of cells. In this lecture, Bridget Carragher will explain the methods used, outline some of the current challenges and discuss opportunities for new advances.
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About the Speaker
Carragher received her Ph.D. in biophysics from the University of Chicago in 1987. She has worked in a variety of positions, both in industry and academia before moving to the New York Structural Biology Center in 2015 to lead the Simons Electron Microscopy Center together with Clint Potter. Carragher and Potter also direct the National Resource for Automated Molecular Microscopy (NRAMM), the National Center for CryoEM Access and Training (NCCAT), and National Center for In-situ Tomographic Ultramicroscopy (NCITU).