Dena Dubal, M.D., Ph.D.Associate Professor, Principal Investigator; David A. Coulter Endowed Chair in Aging and Neurodegenerative Disease, Department of Neurology, University of California, San Francisco
Simons Foundation Lectures are free public colloquia related to basic science and mathematics. These high-level talks are intended for professors, students, postdocs and business professionals, but interested people from the metropolitan area are welcome as well.
Age-related cognitive decline is a major biomedical challenge with no effective medical treatments. Aging affects men and women differently. On average, most women live longer than men worldwide and, in many populations, experience less cognitive decline.
In this lecture, Dena Dubal will discuss the role sex chromosomes play in the aging process. Her group has shown that sex chromosomes contribute to female longevity and resilience in aging and age-related neurodegenerative disease. Specifically, the second X chromosome appears to confer resilience to mortality and to certain aspects of aging. Her group is searching for the fundamental biology that underlies female longevity with the hope to unravel novel targets for aging and disease that could benefit everyone. Their initial clues point to the second X chromosome as a source for new biological pathways that could be harnessed to help both men and women toward the goal of successful brain aging.
Registration is required for this free event.
Further instructions and access to join the webinar will be sent to all registrants upon sign up.