Publications

We study how a suspended liquid film is deformed by an external flow en route to forming a bubble through experiments and a model. We identify a family of nonminimal but stable equilibrium shapes for flow speeds up to a critical value beyond which the film inflates unstably, and the model accounts for the observed nonlinear deformations and forces. A saddle-node or fold bifurcation in the solution diagram suggests that bubble formation at high speeds results from the loss of equilibrium and at low speeds from the loss of stability for overly inflated shapes.

Two-dimensional arrays of periodically driven qubits can host inherently dynamical topological phases with anomalous chiral edge dynamics. These chiral Floquet phases are formally characterized by a dynamical topological invariant, the chiral unitary index. Introducing a quantity called the chiral mutual information, we show that this invariant can be precisely interpreted in terms of a quantized chiral transfer of quantum information along the edge of the system, and devise a physical setup to measure it.

The mammalian kidney develops through reciprocal interactions between the ureteric bud and the metanephric mesenchyme to give rise to the entire collecting system and the nephrons. Most of our knowledge of the developmental regulators driving this process arises from the study of gene expression and functional genetics in mice and other animal models. In order to shed light on human kidney development, we have used single-cell transcriptomics to characterize gene expression in different cell populations, and to study individual cell dynamics and lineage trajectories during development. Single-cell transcriptome analyses of 6414 cells from five individual specimens identified 11 initial clusters of specific renal cell types as defined by their gene expression profile. Further subclustering identifies progenitors, and mature and intermediate stages of differentiation for several renal lineages. Other lineages identified include mesangium, stroma, endothelial and immune cells. Novel markers for these cell types were revealed in the analysis, as were components of key signaling pathways driving renal development in animal models. Altogether, we provide a comprehensive and dynamic gene expression profile of the developing human kidney at the single-cell level.

It is well-known that by placing judiciously chosen image point forces and doublets to the Stokeslet above a flat wall, the no-slip boundary condition can be conveniently imposed on the wall [Blake, J. R. Math. Proc. Camb. Philos. Soc. 70(2), 1971: 303.]. However, to further impose periodic boundary conditions on directions parallel to the wall usually involves tedious derivations because single or double periodicity in Stokes flow may require the periodic unit to have no net force, which is not satisfied by the well-known image system. In this work we present a force-neutral image system. This neutrality allows us to represent the Stokes image system in a universal formulation for non-periodic, singly periodic and doubly periodic geometries. This formulation enables the black-box style usage of fast kernel summation methods. We demonstrate the efficiency and accuracy of this new image method with the periodic kernel independent fast multipole method in both non-periodic and doubly periodic geometries. We then extend this new image system to other widely used Stokes fundamental solutions, including the Laplacian of the Stokeslet and the Rotne-Prager-Yamakawa tensor.

The Experiment to Detect the Global Epoch of Reionization Signature (EDGES) collaboration has reported the detection of an absorption feature in the sky-averaged spectrum at ≈78 MHz. This signal has been interpreted as the absorption of cosmic microwave background (CMB) photons at redshifts 15≲z≲20 by the 21cm hyperfine transition of neutral hydrogen, whose temperature is expected to be coupled to the gas temperature by the Wouthuysen-Field effect during this epoch. Because the gas is colder than the CMB, the 21cm signal is seen in absorption. However, the absorption depth reported by EDGES is more than twice the maximal value expected in the standard cosmological model, at ≈3.8σ significance. Here, we propose an explanation for this depth based on "early dark energy" (EDE), a scenario in which an additional component with equation of state w=−1 contributes to the cosmological energy density at early times, before decaying rapidly at a critical redshift, zc. For 20≲zc≲1000, the accelerated expansion due to the EDE can produce an earlier decoupling of the gas temperature from the radiation temperature than that in the standard model, giving the gas additional time to cool adiabatically before the first luminous sources form. We show that the EDE scenario can successfully explain the large amplitude of the EDGES signal. However, such models are strongly ruled out by observations of the CMB temperature power spectrum. Moreover, the EDE models needed to explain the EDGES signal exacerbate the current tension in low- and high-redshift measurements of the Hubble constant. We conclude that non-finely-tuned modifications of the background cosmology are unlikely to explain the EDGES signal while remaining consistent with other cosmological observations.

We study the field theory for the SU(Nc) symmetric antiferromagnetic quantum critical metal with a one-dimensional Fermi surface embedded in general space dimensions between two and three. The asymptotically exact solution valid in this dimensional range provides an interpolation between the perturbative solution obtained from the epsilon-expansion near three dimensions and the nonperturbative solution in two dimensions. We show that critical exponents are smooth functions of the space dimension. However, physical observables exhibit subtle crossovers that make it hard to access subleading scaling behaviors in two dimensions from the low-energy solution obtained above two dimensions. These crossovers give rise to noncommutativities, where the low-energy limit does not commute with the limits in which the physical dimensions are approached.

The Simons Observatory (SO) is a new cosmic microwave background experiment being built on Cerro Toco in Chile, due to begin observations in the early 2020s. We describe the scientific goals of the experiment, motivate the design, and forecast its performance. SO will measure the temperature and polarization anisotropy of the cosmic microwave background in six frequency bands: 27, 39, 93, 145, 225 and 280 GHz. The initial configuration of SO will have three small-aperture 0.5-m telescopes (SATs) and one large-aperture 6-m telescope (LAT), with a total of 60,000 cryogenic bolometers. Our key science goals are to characterize the primordial perturbations, measure the number of relativistic species and the mass of neutrinos, test for deviations from a cosmological constant, improve our understanding of galaxy evolution, and constrain the duration of reionization. The SATs will target the largest angular scales observable from Chile, mapping ~10% of the sky to a white noise level of 2 μK-arcmin in combined 93 and 145 GHz bands, to measure the primordial tensor-to-scalar ratio, r, at a target level of σ(r)=0.003. The LAT will map ~40% of the sky at arcminute angular resolution to an expected white noise level of 6 μK-arcmin in combined 93 and 145 GHz bands, overlapping with the majority of the LSST sky region and partially with DESI. With up to an order of magnitude lower polarization noise than maps from the Planck satellite, the high-resolution sky maps will constrain cosmological parameters derived from the damping tail, gravitational lensing of the microwave background, the primordial bispectrum, and the thermal and kinematic Sunyaev-Zel'dovich effects, and will aid in delensing the large-angle polarization signal to measure the tensor-to-scalar ratio. The survey will also provide a legacy catalog of 16,000 galaxy clusters and more than 20,000 extragalactic sources

Massive neutrinos uniquely affect cosmic voids. We explore their impact on void clustering using both the DEMNUni and MassiveNuS simulations. For voids, neutrino effects depend on the observed void tracers. As the neutrino mass increases, the number of small voids traced by cold dark matter particles increases and the number of large voids decreases. Surprisingly, when massive, highly biased, halos are used as tracers, we find the opposite effect. How neutrinos impact the scale at which voids cluster and the void correlation is similarly sensitive to the tracers. This scale dependent trend is not due to simulation volume or halo density. The interplay of these signatures in the void abundance and clustering leaves a distinct fingerprint that could be detected with observations and potentially help break degeneracies between different cosmological parameters. This paper paves the way to exploit cosmic voids in future surveys to constrain the mass of neutrinos.

Photon-based spectroscopies have had a significant impact on both fundamental science and applications by providing an efficient approach to investigate the microscopic physics of materials. Together with the development of synchrotron X-ray techniques, theoretical understanding of the spectroscopies themselves and the underlying physics that they reveal has progressed through advances in numerical methods and scientific computing. In this Review, we provide an overview of theories for angle-resolved photoemission spectroscopy and resonant inelastic X-ray scattering applied to quantum materials. First, we discuss methods for studying equilibrium spectroscopies, including first-principles approaches, numerical many-body methods and a few analytical advances. Second, we assess the recent development of ultrafast techniques for out-of-equilibrium spectroscopies, from characterizing equilibrium properties to generating transient or metastable states, mainly from a theoretical point of view. Finally, we identify the main challenges and provide an outlook for the future direction of the field.

The North American Nanohertz Observatory for Gravitational Waves (NANOGrav) has observed dozens of millisecond pulsars for over a decade. We have accrued a large collection of dispersion measure (DM) measurements sensitive to the total electron content between Earth and the pulsars at each observation. All lines of sight cross through the solar wind which produces correlated DM fluctuations in all pulsars. We develop and apply techniques for extracting the imprint of the solar wind from the full collection of DM measurements in the recently released NANOGrav 11-yr data set. We filter out long time scale DM fluctuations attributable to structure in the interstellar medium and carry out a simultaneous analysis of all pulsars in our sample that can differentiate the correlated signature of the wind from signals unique to individual lines of sight. When treating the solar wind as spherically symmetric and constant in time, we find the electron number density at 1 A.U. to be 7.9±0.2 cm−3. Our data shows little evidence of long-term variation in the density of the wind. We argue that our techniques paired with a high cadence, low radio frequency observing campaign of near-ecliptic pulsars would be capable of mapping out large-scale latitudinal structure in the wind.