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Imaging as Exploration

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

Advanced data generation capabilities require other enhanced abilities — with increasing data size and complexity, the development of more efficient acquisition and analysis methods is essential. In this lecture, Lawrence R. Frank will discuss how this new paradigm of imaging exploration is manifest.

Illuminating Biology at the Nanoscale with Super-Resolution Florescence Microscopy

Stochastic optical reconstruction microscopy (STORM), breaks the diffraction limit on light microscopy by using selective activation of photo-switchable fluorescent probes to temporally separate the spatially overlapping images of individual molecules. This approach has allowed multicolor and 3-D imaging of living cells with nanometer-scale resolution, enabling discoveries of novel sub-cellular structures. In this talk, Prof. Zhuang will discuss her group's development of STORM and its biological applications.

Extra-Solar Planets: Search, Characterization and Population Inferences

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

David W. Hogg will explore how planets are discovered in the Kepler dataset, how the data are understood and how researchers can make inferences about the full population of planets in the galaxy.

Solving the 3-D Puzzle of Rotation Assignment in Single Particle Cryo-Electron Microscopy

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

This lecture will explore algorithms for estimating the unknown pose parameters. The main focus will be on algorithms that are based on semidefinite programming relaxations that can be viewed as extensions to existing approximation algorithms to max-cut and unique games, two fundamental problems in theoretical computer science.


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