Harnessing Hippocampal Stem Cells to Improve Mood and Cognition
Recent studies have implicated adult-born hippocampal neurons in pattern separation, a process by which similar experiences or events are transformed into discrete non-overlapping representations. Impaired pattern separation, Dr. Hen proposes, underlies the overgeneralization often seen in age-related memory impairments and in anxiety disorders. Dr. Hen will present evidence that strategies aimed at stimulating hippocampal neurogenesis result in improved pattern separation.