Graeme Davis received his B.A. at Williams College in 1989 and a Ph.D. from the University of Massachusetts in 1994. He pursued a postdoctoral fellowship at the University of California, Berkeley, under the guidance of Core S. Goodman. In 1998, he began his independent academic career as an assistant professor at the University of California, San Francisco, School of Medicine. Davis has remained at UCSF his entire career and is currently the Morris Hertzstein Distinguished Professor of Medicine and the former chairman of the department of biochemistry and biophysics. He and his laboratory have pioneered the field of homeostatic plasticity, beginning with work published in the mid-1990s and continuing to this day. They have taken advantage of genome-scale forward genetics screens in model organisms to define a majority of genes currently known to control the homeostatic regulation of neurotransmitter release and ion channel gene expression. Recently, the Davis lab has turned its attention to the interface of homeostatic plasticity and the mechanisms of neurological and psychiatric disease.