From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others
An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning
Andrew McKay, Chi-Kuo Hu, Sharon Chen, Claire Nicole Bedbrook, Mike Thielvoldt, Tony Wyss-Coray and Anne Brunet
bioRxiv posted 31 March 2021
Functional architecture of the aging brain
Roni Setton, Laetitia Mwilambwe-Tshilobo, Manesh Girn, Amber W. Lockrow, Giulia Baracchini, Alexander J. Lowe, Benjamin N. Cassidy, Jian Li, Wen-Ming Luh, Danilo Bzdok, Richard M. Leahy, Tian Ge, Daniel S. Margulies, Bratislav Misic, Boris C. Bernhardt, W. Dale Stevens, Felipe De Brigard, Prantik Kundu, Gary R. Turner, and R. Nathan Spreng
bioRxiv posted 31 March 2021
Aging is associated with a degeneration of noradrenergic-, but not dopaminergic-neurons, in the short-lived killifish Nothobranchius furzeri.
Sara Bagnoli, Baldassare Fronte, Carlo Bibbiani, Eva Terzibasi Tozzini, and Alessandro Cellerino
bioRxiv posted 31 March 2021
Chromatin accessibility dynamics of neurogenic niche cells reveal a reversible decline in neural stem cell migration during aging
Robin W Yeo, Olivia Y Zhou, Brian Zhong, Mahfuza Sharmin, Tyson J Ruetz, Anshul Kundaje, Alexander R Dunn, and Anne Brunet
bioRxiv posted 29 March 2021
Sex-specific life extension in tauopathy mice by CSF1R inhibition causing selective microglial depletion and suppressed pathogenesis
Noah R Johnson, Peng Yuan, T Peter Lopez, Weizhou Yue, Annalise Bond, Brianna M Rivera, Masakazu Hirouchi, Kurt Giles, Atsushi Aoyagi, and Carlo Condello
bioRxiv posted 22 March 2021
Dopamine and reward-related vigor in younger and older human participants
Emily J Hird, Ulrik Beierholm, Lieke De Boer, Jan Axelsson, Katrine Riklund, Lars Nyberg, Lars Beckman, and Marc Guitart-Masip
bioRxiv posted 19 March 2021
Neural correlates of metacognition across the adult lifespan
Helen Overhoff, Yiu Hong Ko, Daniel Feuerriegel, Gereon R. Fink, Jutta Stahl, Peter H. Weiss, Stefan Bode, and Eva Niessen
bioRxiv posted 17 March 2021
Sex-specific interactions between procedural and deliberative decision-making systems in a mouse model of Alzheimer’s disease
Rachel Anderson, Damyan W Hart, Brian Sweis, Mathew A Sherman, Mark Thomas, David David Redish, and Sylvain Lesne
bioRxiv posted 17 March 2021
Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and expansion of the neural stem cell population
James Catlin, Leandro N Marziali, Benjamin Rein, Zhen Yan, M Laura Feltri, and Christine Schaner Tooley
bioRxiv posted 16 March 2021
Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging
Sebastian Jessberger and John Cole
bioRxiv posted 4 March 2021
MEG Oscillatory and Aperiodic neural dynamics contribute to different cognitive aspects of short-term memory decline through the lifespan
Kusum Thuwal, Arpan Banerjee, and Dipanjan Roy
bioRxiv posted 2 March 2021
