From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

Age-related changes in neural synchronization and the sustained response to amplitude and frequency modulation of sound

Bjorn Herrmann, Burkhard Maess, and Ingrid S. Johnsrude

bioRxiv posted 29 April 2022

[Abstract] [PDF]

 

Deficiency in pericyte remodeling as a basis for impaired capillary flow and structure during brain aging

Andree-Anne Berthiaume, Franca Schmid, Stefan Stamenkovic, Vanessa Santos, Cara Nielson, Bruno Weber, Mark Majesky, and Andy Shih

bioRxiv posted 29 April 2022

[Abstract] [PDF]

 

Older circuits get richer: neurogenesis timeline shapes hubness and neurogenetic profiles of the adult human brain

Ibai diez, Fernando Garcia Moreno, Nayara Carral Sainz, Sebastiano Stramaglia, Alicia Nieto Reyes, Mauro D’Amato, Jesus M Cortes, and paolo bonifazi

bioRxiv posted 29 April 2022

[Abstract] [PDF]

 

Global brain health modulates the impact of lesion damage on post-stroke sensorimotor outcomes

Sook-Lei Liew, Nicolas Schweighofer, James H Cole, Artemis Zavaliangos-Petropulu, Bethany P Lo, Laura KM Han, Tim Hahn, Lianne Schmaal, Miranda R Donnelly, Jessica N Jeong, Zhizhuo Wang, Aisha Abdullah, Jun H Kim, Alexandre Hutton, Giuseppe Barisano, Michael R Borich, Lara A Boyd, Amy Brodtmann, Cathrin M Buetefisch, Winston D Byblow, Jessica M Cassidy, Charalambos C Charalambous, Valentina Ciullo, Adriana B Conforto, Rosalia Dacosta-Aguayo, Julie A DiCarlo, Martin Domin, Adrienne N Dula, Natalia Egorova-Brumley, Wuwei Feng, Fatemeh Geranmayeh, Chris M Gregory, Colleen A Hanlon, Jess A Holguin, Brenton Hordacre, Neda Jahanshad, Steven A Kautz, Mohamed Salah Khlif, Hosung Kim, Amy Kuceyeski, David J Lin, Jingchun Liu, Martin Lotze, Bradley J MacIntosh, John L Margetis, Maria Mataro, Feroze B Mohamed, Emily R Olafson, Gilsoon Park, Fabrizio Piras, Kate P Revill, Pamela Roberts, Andrew D Robertson, Nerses Sanoss ian, Heidi M Schambra, Na Jin Seo, Surjo R Soekadar, Gianfranco Spalletta, Cathy M Stinear, Myriam Taga, Wai Kwong Tang, Greg T Thielman, Daniela Vecchio, Nick S Ward, Lars T Westlye, Carolee J Winstein, George F Wittenberg, Steven L Wolf, Kristin A Wong, Chunshui Yu, Steven C Cramer, and Paul Thompson

bioRxiv posted 29 April 2022

[Abstract] [PDF]

 

Age-related changes of deep-brain neurophysiological activity

Thomas T Hinault, Sylvain T Baillet, and Susan Courtney

bioRxiv posted 28 April 2022

[Abstract] [PDF]

 

Blood-brain barrier dysfunction promotes astrocyte senescence through albumin-induced TGFβ signaling activation

Marcela Preininger, Dasha Zaytseva, Jessica May Lin, and Daniela Kaufer

bioRxiv posted 28 April 2022

[Abstract] [PDF]

 

A Quantum Dot Biomimetic for SARS-CoV-2 to Interrogate Dysregulation of the Neurovascular Unit Relevant to Brain Inflammation

Wesley Chiang, Angela Litzburg, Francine Yanchik-Slade, Herman Li, Bradley L. Nilsson, Harris A Gelbard, and Todd D Krauss

bioRxiv posted 22 April 2022

[Abstract] [PDF]

 

Functional Specialization of Parallel Distributed Networks Revealed by Analysis of Trial-to-Trial Variation in Processing Demands

Lauren M DiNicola, Oluwatobi I Ariyo and Randy L Buckner

bioRxiv. posted 20 April 2022

[Abstract]

 

Fleeting Effects of Incentives: Adult Age Differences in ERP Measures of Motivated Attention

Margot D. Sullivan, Farrah Kudus, Ben Dyson, and Julia Spaniol

bioRxiv posted 18 April 2022

[Abstract] [PDF]

 

Persistent post-COVID-19 smell loss is associated with inflammatory infiltration and altered olfactory epithelial gene expression

John B Finlay, David H Brann, Ralph Abi Hachem, David W Jang, Allison D Oliva, Tiffany Ko, Rupali Gupta, Sebastian A Wellford, E Ashley Moseman, Sophie S Jang, Carol H Yan, Hiroaki Matsunami, Tatsuya Tsukahara, Sandeep Robert Datta, and Bradley J Goldstein

bioRxiv posted 18 April 2022

[Abstract] [PDF]

 

A Third Somatomotor Representation in the Human Cerebellum

Noam Saadon-Grosman, Peter A Angeli, Lauren M DiNicola and Randy L Buckner

bioRxiv. posted 14 April 2022

[Abstract]

 

Age-related changes in the neural mechanics of dynamic auditory attention in time

Bjorn Herrmann, Burkhard Maess, Molly J. Henry, Jonas Obleser, and Ingrid S. Johnsrude

bioRxiv posted 13 April 2022

[Abstract] [PDF]

 

Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons

Maria A Telpoukhovskaia, Niran Hadad, Brianna Gurdon, Miko Dai, Andrew R Ouellette, Sarah M Neuner, Amy R Dunn, Shania Hansen, Yiyang Wu, Logan Dumitrescu, Kristen M.S. O’Connell, Eric B Dammer, Nicholas T Seyfried, Sukalp Muzumdar, Jesse Gillis, Paul Robson, Ji-Gang Zhang, Timothy J. Hohman, Vivek Philip, Vilas Menon and Catherine C Kaczorowski

bioRxiv. posted 13 April 2022

[Abstract]

 

Larger and more dentated hippocampal structure is associated with better memory in the oldest-old.

Vuga Parpura, Hector Caceres, Sara Sims, Lawrence Ver Hoef, Anandh K Ramaniharan, Stacy Merritt, Roxanne F Rezaei, Pradyumna K Bharadwaj, Mary Kate Franchetti, David A Raichlen, Courtney J Jessup, Alex G Hinshaw, Emily J Van Etten, Theodore P Trouard, David S Geldmacher, Virginia G Wadley, Noam Alperin, Eric S Porges, Adam J Woods, Ron A Cohen, Bonnie E Levin, Tatjana Rundek, Gene E Alexander, and Kristina M Visscher

bioRxiv posted 11 April 2022

[Abstract] [PDF]

 

Life-long Dietary Restrictions have Negligible or Damaging Effects on Late-life Cognitive Performance: A Key Role for Genetics in Outcomes

Andrew R Ouellette, Niran Hadad, Andrew Deighan, Laura Robinson, Kristen M.S. O’Connell, Adam Freund, Gary A Churchill and Catherine Kaczorowski

bioRxiv. posted 10 April 2022

[Abstract]

 

Unexpected proteinopathies in hippocampal PDE11A4 promote age-related cognitive decline of social associative memories

Kaitlyn ( Pilarzyk, Latarsha Porcher, William R. Capell, Steven D. Burbano, Jeffrey Davis, Janet Fisher, Nicole Gorny, Siena Petrolle, and Michy P. Kelly

bioRxiv posted 10 April 2022

[Abstract] [PDF]

 

Less is more – loss of EGFL7 improves memory by upregulation of VEGF-D

Mirko HH Schmidt, Verica Vasic, Kathrin Barth, Frank Bicker, Ulrike Schumann, Christine Maurer, Nora Heinig, Cora Roehlecke, Ute Nimtschke, Lana Schumann, Matthias Meinhardt, Thomas Mittmann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, and Irmgard Tegeder

bioRxiv posted 10 April 2022

[Abstract] [PDF]

 

Liver-secreted fluorescent blood plasma markers enable chronic imaging of microcirculation

Xiaowen Wang, Christine Delle, Antonis Asiminas, Sonam Akther, Marta Vittani, Peter Brogger, Peter Kusk, Camilla Trang Vo, Ayumu Konno, Hirokazu Hirai, Masahiro Fukuda, Pia Weikop, Steven Alan Goldman, Maiken Nedergaard and Hajime Hirase

bioRxiv. posted 10 April 2022

[Abstract]

 

DeepParcellation: a novel deep learning method for robust brain magnetic resonance imaging parcellation in older East Asians

Eun-Cheon Lim, Uk-Su Choi, Kyu Yeong Choi, Jang Jae Lee, Yul-Wan Sung, Seiji Ogawa, Byeong Chae Kim, Kun Ho Lee, Jungsoo Gim, and the Alzheimer’s Disease Neuroimaging Initiative

bioRxiv posted 9 April 2022

[Abstract] [PDF]

 

Cochlear Neurotrophin-3 overexpression at mid-life prevents age-related cochlear synaptopathy and slows age-related hearing loss

Luis R Cassinotti, Lingchao Ji, Beatriz C Borges, Nathan D Cass, Aditi S Desai, David C Kohrman, M. Charles Liberman, and Gabriel Corfas

bioRxiv posted 8 April 2022

[Abstract] [PDF]

 

A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during ageing and in Alzheimer’s disease

Megan E Jones, Johanna Buechler, Tom Dufor, Katharina Boroviak, Emmanouil Metzakopian, Alasdair Gibb, and Patricia C Salinas

bioRxiv posted 8 April 2022

[Abstract] [PDF]

 

Microglia Detect Externalized Phosphatidylserine on Synapses for Elimination via TREM2 in Alzheimer’s Disease Models

Javier Rueda-Carrasco, Dimitra Sokolova, Sang-Eun Lee, Thomas Childs, Natalia Jurcakova, Sebastiaan De Schepper, Judy Z. Ge, Joanne I. Lachica, Christina E. Toomey, Oliver J. Freeman, John Hardy, Beth Stevens, Tammaryn Lashley, Sunghoe Chang and Soyon Hong

bioRxiv. posted 5 April 2022

[Abstract]

 

Affective enhancement of episodic memory is associated with widespread patterns of intrinsic functional connectivity across the adult lifespan

Yuta Katsumi and Matthew Moore

bioRxiv posted 1 April 2022

[Abstract] [PDF]

 

The role of clearance in neurodegenerative diseases

Georgia S Brennan, Travis B Thompson, Hadrien Oliveri, Marie E Rognes, and Alain Goriely

bioRxiv posted 1 April 2022

[Abstract] [PDF]

 

History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause

Nina E Baumgartner, Shannon M McQuillen, Samantha F Perry, Sangtawan Miller, Robert Gibbs and Jill M Daniel

bioRxiv. posted 1 April 2022

[Abstract]

 

 

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