The Biophysical Modeling group focuses on the modeling and simulation of complex systems that arise in biology and soft condensed matter physics.
Areas of interest include the dynamics of complex and active materials, and aspects of collective behavior and self-assembly in both natural systems (e.g., inside the cell) and synthetic ones. Our approach is based on mathematical modeling and analysis, the development and application of software tools for large-scale biophysical simulation, and close collaboration with experimentalists.
The 3D spatiotemporal organization of the human genome inside the cell nucleus remains a major open question in cellular biology.…BioRxiv
Measuring and modeling polymer concentration profiles near spindle boundaries argues that spindle microtubules regulate their own nucleation
Abstract Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by…New Journal of Physics
Florencio Balboa Usabiaga joined the foundation in 2017 as a member of the Biophysical Modeling group. He is interested in the development of tools for fluctuating hydrodynamics and Brownian dynamics simulations. At the foundation, he works to extend these methods to explore relevant biophysical phenomena,…
Enkeleida Lushi joined the Simons Foundation in 2017 as part of the Biophysical Modeling group, where she develops mathematical models and efficient simulation techniques to trace the collective dynamics of large ensembles of active and driven particles in complex geometries and flow conditions. Dr. Lushi…
Wen Yan joined the Simons Foundation in 2016 as part of CCB’s biophysical modeling group. His research focuses on the development and simulation of mathematical models pertaining to phenomena in biophysics and active materials and the development of simulations of suspensions of such active objects.