Center for Computational Biology

Biomolecular Design The theory of protein folding explains how a disordered chain of amino acids spontaneously adopts a well-defined three-dimensional structure in water. The ultimate test of a theory is its successful application to the design of new physical systems with new, desired properties. In the Biomolecular Design Group, we apply the theory of protein folding to design new heteropolymers that fold into well-defined three-dimensional structures with new, useful functions, but which are built from exotic chemical building-blocks that go beyond the 20 canonical amino acids that make up natural proteins.
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