Biological Transport Networks The Biological Flow Networks Group employs theoretical and computational methodologies to elucidate the underlying principles governing the evolution, development and functionality of biological flow networks, such as arterial, venous, and lymphatic systems and biological transport systems in general.

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Biomolecular Design The theory of protein folding explains how a disordered chain of amino acids spontaneously adopts a well-defined three-dimensional structure in water. The ultimate test of a theory is its successful application to the design of new physical systems with new, desired properties. In the Biomolecular Design Group, we apply the theory of protein folding to design new heteropolymers that fold into well-defined three-dimensional structures with new, useful functions, but which are built from exotic chemical building-blocks that go beyond the 20 canonical amino acids that make up natural proteins.

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Biophysical Modeling The Biophysical Modeling group focuses on the modeling and simulation of complex systems that arise in biology and soft condensed matter physics. Areas of interest include the dynamics of complex and active materials, as well as aspects of collective behavior and self-organization in both natural systems (e.g., inside the cell) and synthetic ones.

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Developmental Dynamics The Developmental Dynamics group combines experiments, theory and computing to elucidate the contributions of encoded genomic instructions and self-organizing physical mechanisms to embryonic development.

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Genomics An immensely complex molecular network of interactions forms the foundation of human biology and disease. Genomic approaches provide a particularly illuminating window to biological systems, and when combined with advanced analysis allow us to learn and model this complexity.

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Structural and Molecular Biophysics Underlying all biological processes are molecules and their interactions with each other. However, our ability to understand how these molecules function over biologically relevant scales remains very limited.

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