Center for Computational Biology

Simons Foundation

The Center for Computational Biology develops new and innovative methods of examining data in the biological sciences whose scale and complexity have historically resisted analysis.

CCB’s mission is to develop modeling tools and theory for understanding biological processes and to create computational frameworks that will enable the analysis of the large, complex data sets being generated by new experimental technologies.

Groups

Biophysical Modeling The Biophysical Modeling group focuses on the modeling and simulation of complex systems that arise in biology and soft condensed matter physics. Read More

Genomics An immensely complex molecular network of interactions forms the foundation of human biology and disease. Genomic approaches provide a particularly illuminating window to biological systems, and when combined with advanced analysis allow us to learn and model this complexity. Read More

Neuroscience Our goal is to understand how the brain analyzes large and complex datasets streamed by sensory organs in order to aid efforts at building artificial neural systems and treating mental illness. Read More

Systems Biology At the Systems Biology group, we are developing new methods to learn the networks that run life’s program. Read More

News & Announcements

July 08, 2019

Building a Network That Learns Like We Do

July 02, 2019

Toward a Grand Unified Theory of Spindles

May 27, 2019

New Causes of Autism Found in ‘Junk’ DNA By Thomas Sumner

Upcoming Events

August 2019

26 Mon
- Meeting 10:00 AM - 12:00 PM
  Biophysical Modeling Group Meeting
27 Tue
- Lecture 1:15 - 2:15 PM
  Brown Bag Seminar
  
  Kathleen ChenData Scientist, Genomics, CCB, Flatiron Institute
29 Thu
- Meeting 1:00 - 2:15 PM
  Neuroscience Group Meeting

September 2019

02 Mon
- Meeting 10:00 AM - 12:00 PM
  Biophysical Modeling Group Meeting
04 Wed
- Meeting 12:00 - 2:30 PM
  Genomics Group Meeting
05 Thu
- Meeting 1:00 - 2:15 PM
  Neuroscience Group Meeting
09 Mon
- Meeting 10:00 AM - 12:00 PM
  Biophysical Modeling Group Meeting
10 Tue
- Seminar 1:15 - 2:15 PM
  Brown Bag Seminar
12 Thu
- Meeting 1:00 - 2:15 PM
  Neuroscience Group Meeting
16 Mon
- Meeting 10:00 AM - 12:00 PM
  Biophysical Modeling Group Meeting

Research Highlights

July 4, 2019

Current approaches for the analysis of spindle organization

S Redemann, S. Fürthauer, M. Shelley, T Müller-Reichert

The organization of microtubules in spindles is complex and not fully understood. Here we report on current advances in generating…

Current opinion in structural biology

2019

Complex dynamics of long, flexible fibers in shear

John LaGrone, Ricardo Cortez, W. Yan, Lisa Fauci

The macroscopic properties of polymeric fluids are inherited from the material properties of the fibers embedded in the solvent. The…

Journal of Non-Newtonian Fluid Mechanics

June 1, 2019

Convergent solutions of Stokes Oldroyd-B boundary value problems using the Immersed Boundary Smooth Extension (IBSE) method

D. Stein, RD Guy, B Thomases

The Immersed Boundary (IB) method has been widely used to solve fluid-structure interaction problems, including those where the structure interacts…

Journal of Non-Newtonian Fluid Mechanics

Director

Michael Shelley, Ph.D.

Director, CCB

Michael Shelley joined the Simons Foundation in 2016 to work on the modeling and simulation of complex systems arising in physics and biology.

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