From the bioRxiv: A Selection of Recently Posted Papers from SCPAB Investigators and Others

Each month, SCPAB scans the bioRxiv and arXiv for interesting papers from the SCPAB community and beyond.

Cortical thickness, gray matter volume and cognitive performance: a cross-sectional study of the moderating effects of age on their inter-relationships

Marianne de Chastelaine, Sabina Srokova, Mingzhu Hou, Amber Kidwai, Seham Kafafi, Melanie Racenstein, and Michael Rugg

bioRxiv posted 2 October 2022

[Abstract] [PDF]

 

A single-cell multi-omic atlas spanning the adult rhesus macaque brain

Kenneth L Chiou, Xingfan Huang, Martin O Bohlen, Sebastien Tremblay, Diana R O’Day, Cailyn H Spurrell, Aishwarya A Gogate, Trisha M Zintel, Cayo Biobank Research Unit, Madeline G Andrews, Melween I Martinez, Lea M Starita, Michael J Montague, Michael L Platt, Jay Shendure and Noah Snyder-Mackler

bioRxiv. posted 3 October 2022

[Abstract]

 

Motor imagery training is beneficial for motor memory of upper and lower limb tasks in very old adults

Pauline M Hilt, Mathilde Bertrand, Leonard Feasson, Florent Lebon, France Mourey, Celia Ruffino, and Vianney Rozand

bioRxiv posted 4 October 2022

[Abstract] [PDF]

 

The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice

Luke D Roberts, Amanda K. E. Hornsby, Alanna Thomas, Martina Sassi, Aimee Kinzett, Nathan Hsiao, Bethan R David, Mark Good, Timothy Wells, and Jeffrey S Davies

bioRxiv posted 6 October 2022

[Abstract] [PDF]

 

The vertical position of visual information conditions spatial memory performance in healthy aging

Marion Durteste, Louise Van Poucke, Sonia Combariza, Bilel Abderrahmane Benziane, José-Alain Sahel, Stephen Ramanoël, and Angelo Arleo

bioRxiv posted 7 October 2022

[Abstract] [PDF]

 

Free-water volume fraction increases non-linearly with age in the white matter of the healthy human brain

Tomasz Pieciak, Guillem París, Dani Beck, Ivan Maximov, Antonio Tristán-Vega, Rodrigo de Luis-García, Lars T. Westlye, and Santiago Aja-Fernández

bioRxiv posted 7 October 2022

[Abstract] [PDF]

 

Optic radiations representing different eccentricities age differently

John Kruper, Noah C Benson, Sendy Caffarra, Julia P Owen, Yue Wu, Aaron Y Lee, Cecilia S Lee, Jason D Yeatman, and Ariel Rokem

bioRxiv posted 7 October 2022

[Abstract] [PDF]

 

GABA decrease is associated with degraded neural specificity in the visual cortex of glaucoma patients

Ji Won Bang, Carlos Parra, Kevin Yu, Gadi Wollstein, Joel Schuman, and Kevin Chan

bioRxiv posted 12 October 2022

[Abstract] [PDF]

 

Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition

Shreya Chakraborty and Bratati Kahali

bioRxiv. posted 14 October 2022

[Abstract]

 

Network Segregation in Aging Females and Evaluation of the Impact of Sex Steroid Hormones

Tracey H Hicks, Thamires N.C. Magalhaes, Hannah K Ballard, T. Bryan Jackson, Sydney J. Cox, and Jessica A. Bernard

bioRxiv posted 16 October 2022

[Abstract] [PDF]

 

Electrophysiological signatures of targeted memory reactivation during sleep are not accompanied by motor performance improvements in older adults

Judith Nicolas, Julie Carrier, Stephan Swinnen, Julien Doyon, Genevieve Albouy, and Bradley Ross King

bioRxiv posted 17 October 2022

[Abstract] [PDF]

 

The integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance

Martin J. Dahl, Shelby L Bachman, Shubir Dutt, Sandra Duezel, Nils C. Bodammer, Ulman Lindenberger, Simone Kuehn, Markus Werkle-Bergner, and Mara Mather

bioRxiv posted 17 October 2022

[Abstract] [PDF]

 

Myeloid deficiency of the intrinsic clock protein Bmal1 accelerates cognitive aging by disrupting microglial synaptic pruning

Chinyere Agbaegbu Iweka, Erica Michelle Seigneur, Amira Latif Hernandez, Sur Herrera Paredes, Mica Cabrera, Eran Blacher, Connie Pasternak, Frank Longo, Luis de Lecea and Katrin Andreasson

bioRxiv. posted 18 October 2022

[Abstract]

 

Facilitatory stimulation of the pre-SMA in healthy aging has distinct effects on task-based activity and connectivity

Sandra Martin, Regine Frieling, Dorothee Saur, and Gesa Hartwigsen

bioRxiv posted 21 October 2022

[Abstract] [PDF]

 

Inherent envelope fluctuations in forward masking: Effects of age and hearing loss

Marc Brennan, Adam Svec, Afagh Farhadi, Braden Maxwell, and Laurel H Carney

bioRxiv posted 21 October 2022

[Abstract] [PDF]

 

Facilitatory stimulation of the pre-SMA in healthy aging has distinct effects on task-based activity and connectivity

Sandra Martin, Regine Frieling, Dorothee Saur and Gesa Hartwigsen

bioRxiv. posted 21 October 202

[Abstract]

 

Persistent Homology-based Functional Connectivity Explains Cognitive Ability: Life-span Study

Hyunnam Ryu, Christian G Habeck, Yaakov Stern, and Seonjoo Lee

bioRxiv posted 21 October 2022

[Abstract] [PDF]

 

Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies

Ariel K Frame, J. Wesley Robinson, Nader H. Mahmoudzadeh, Jason M. Tennessen, Anne F. Simon, and Robert C. Cumming

bioRxiv posted 21 October 2022

[Abstract] [PDF]

 

Adult lifespan trajectories of neuromagnetic signals and interrelations with cortical thickness

Christina Stier, Christoph Braun, and Niels K. Focke

bioRxiv posted 24 October 2022

[Abstract] [PDF]

 

LTP-like noninvasive striatal brain stimulation enhances striatal activity and motor skill learning in humans

Maximilian J. Wessel, Elena Beanato, Traian Popa, Fabienne Windel, Pierre Vassiliadis, Pauline Menoud, Valeriia Beliaeva, Ines R. Violante, Hedjoudje Abderrahmane, Patrycja Dzialecka, Chang-Hyun Park, Pablo Maceira-Elvira, Takuya Morishita, Antonino Cassara, Melanie Steiner, Nir Grossman, Esra Neufeld, and Friedhelm C. Hummel

bioRxiv posted 28 October 2022

[Abstract] [PDF]

 

Chronic intermittent propofol attenuates surgery-induced neuroinflammation, apoptosis, and cognitive impairment in aged mice

Rajasekar Nagarajan, Jinrui Lyu, Maltesh Kambali, Muxiao Wang, Robert A. Pearce, and Uwe Rudolph

bioRxiv posted 28 October 2022

[Abstract] [PDF]

 

Mixed Models Quantify Annual Volume Change; Linear Regression Determines Thalamic Volume as the Best Subcortical Structure Volume Predictor in Alzheimer’s Disease and Aging

Charles S Leger, Monique Herbert, W Dale Stevens, and Joseph F DeSouza

bioRxiv posted 31 October 2022

[Abstract] [PDF]

 

Transcription, structure, and organoids translate time across the lifespan of humans and great apes

Christine J Charvet, Kwadwo Ofori, Carmen Falcone, and Brier A Rigby Dames

bioRxiv posted 31 October 2022

[Abstract] [PDF]

 

Aging impairs astrocytes in the human cerebral cortex

Alexander Popov, Nadezda Brazhe, Kseniia Morozova, Konstantin Yashin, Maxim Bychkov, Olga Nosova, Oksana Sutyagina, Alexey Brazhe, Evgenia Parshina, Li Li, Igor Medyanik, Dmitry E Korzhevskii, Zakhar Shenkarev, Ekaterina Lyukmanova, Alexei Verkhratsky, and Alexey Semyanov

bioRxiv posted 1 November 2022

[Abstract] [PDF]

 

Genetic ablation of dentate hilar somatostatin-positive GABAergic interneurons is sufficient to induce cognitive impairment

Rajasekar Nagarajan, Jinrui Lyu, Maltesh Kambali, Muxiao Wang, Connor D. Courtney, Catherine A. Christian-Hinman, and Uwe Rudolph

bioRxiv posted 2 November 2022

[Abstract] [PDF]

 

Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders

Laura A Cox, Sobha Puppala, Jeannie Chan, Kip Zimmerman, Zeeshan Hamid, Isaac Ampong, Hillary F Huber, Ge Li, Avinash YL Jadhav, Benlian Wang, Cun Li, Carol Shively, Geoffrey Clarke, Thomas C Register, Peter W Nathanielsz and Michael Olivier

bioRxiv. posted 2 November 2022

[Abstract]

 

A generalizable epigenetic clock captures aging in two nonhuman primates.

Elisabeth A Goldman, Marina M Watowich, Kenneth L Chiou, Arianne Mercer, Sierra N Sams, Julie E Horvath, Jordan Anderson, Cayo Biobank Research Unit, Jenny Tung, James P Higham, Lauren JN Brent, Melween I Martinez, Michael James Montague, Michael L Platt, Kirstin N Sterner and Noah Snyder-Mackler

bioRxiv. posted 2 November 2022

[Abstract]

 

Network Occlusion Sensitivity Analysis Identifies Regional Contributions to Brain Age Prediction

Lingfei He, Cheng Chen, Yaping Wang, Qingcheng Fan, Congying Chu, Junhai Xu, and Lingzhong Fan

bioRxiv posted 3 November 2022

[Abstract] [PDF]

 

Age-related changes in brain metabolites underlie slowing of speed-accuracy trade-off

Lauren Revie and Claudia Metzler-Baddeley

bioRxiv posted 3 November 2022

[Abstract] [PDF]

 

Musical expertise enhances neural alignment-to-young in sensorimotor regions that predicts older adults’ audiovisual speech-in-noise perception

Lei Zhang, Xiuyi Wang, and Yi Du

bioRxiv posted 5 November 2022

[Abstract] [PDF]

 

Neural Entrainment to Musical Pulse In Naturalistic Music Is Preserved In Aging: Implications for Music-Based Interventions

Parker Tichko, Nicole Page, Ji Chul Kim, Edward Large, and Psyche Loui

bioRxiv posted 6 November 2022

[Abstract] [PDF]

 

Age-related changes in ‘cortical’ 1/f dynamics are explained by cardiac activity

Fabian Schmidt, Sarah K. Danboeck, Eugen Trinka, Gianpaolo Demarchi, and Nathan Weisz

bioRxiv posted 7 November 2022

[Abstract] [PDF]

 

Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex

Masashi Fujita, Zongmei Gao, Lu Zeng, Cristin McCabe, Charles C White, Bernard Ng, Gilad Sahar Green, Orit Rozenblatt-Rosen, Devan Phillips, Liat Amir-Zilberstein, Hyo Lee, Richard V Pearse II, Atlas Khan, Badri N Vardarajan, Krzysztof Kiryluk, Chun Jimmie Ye, Hans-Ulrich Klein, Gao Wang, Aviv Regev, Naomi Habib, Julie A Schneider, Yanling Wang, Tracy Young-Pearse, Sara Mostafavi, David A Bennett, Vilas Menon and Phillip L De Jager

bioRxiv. posted 8 November 2022

[Abstract]

 

Investigation of the neural effects of memory training to reduce false memories in older adults: Univariate and multivariate analyses

Indira C Turney, Jordan D Chamberlain, Jonathan G Hakun, Ashley C Steinkrauss, Lesley A Ross, Brenda A Kirchhoff, and Nancy A Dennis

bioRxiv posted 9 November 2022  [Abstract] [PDF]

 

Estimation of Vertex-wise Sulcal Width Maps on Cortical Surfaces

Alberto Fernandez-Pena, Francisco J. Navas-Sanchez, Daniel Martin de Blas, Luis Marcos-Vidal, Pedro M. Gordaliza, Isabel Martinez-Tejada, Joost Janssen, Susanna Carmona, Manuel Desco, and Yasser Aleman-Gomez

bioRxiv posted 9 November 2022

[Abstract] [PDF]

 

Epigenetic age acceleration predicts subject-specific white matter degeneration in the human brain.

Benjamin T Newman, Joshua S Danoff, Morgan E Lynch, Stephanie Giamberardino, Simon G Gregory, Jessica J Connelly, T Jason Druzgal, and James P Morris

bioRxiv posted 14 November 2022

[Abstract] [PDF]

 

Brain-age prediction: a systematic comparison of machine learning workflows

Shammi More, Georgios Antonopoulos, Felix Hoffstaedter, Julian Caspers, Simon B. Eickhoff, and Kaustubh R. Patil

bioRxiv posted 17 November 2022

[Abstract] [PDF]

 

Multi-‘Omic Integration via Similarity Network Fusion to Detect Molecular Subtypes of Aging

Mu Yang, Stuart Matan-Lithwick, Yanling Wang, Phillip De Jager, David A Bennett and Daniel Felsky

bioRxiv. posted 17 November 2022

[Abstract]

 

Neural noise is associated with age-related neural dedifferentiation

Rachelle E Pichot, Daniel J. Henreckson, Morgan Foley, and Joshua D Koen

bioRxiv posted 18 November 2022

[Abstract] [PDF]

 

BrainAGE revisited: Keeping up the pace with deep learning methods

Polona Kalc, Robert Dahnke, Felix Hoffstaedter, and Christian Gaser

bioRxiv posted 22 November 2022

[Abstract] [PDF]

 

Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

Courtney Glavis-Bloom, Casey R Vanderlip, Sammy Weiser Novak, Masaaki Kuwajima, Lyndsey Kirk, Uri Manor, Kristen M Harris, and John H Reynolds

bioRxiv posted 28 November 2022

[Abstract] [PDF]

 

Openness to experience is associated with neural and performance measures of memory in older adults

Christopher Stolz, Ariane Bulla, Joram Soch, Bjoern Hendrik Schott, and Anni Richter

bioRxiv posted 29 November 2022

[Abstract] [PDF]

 

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